The kinetics of increased Treg frequencies coincided with the kinetics of lymphoma cell appearance in the three tissues (day 8 in the LNs, day 6 in bone marrow and spleen), but not in blood, where only modest Treg increases were visible, and only with a 3-day delay at day 9 (figure 5A,B, online supplemental figure S4A,B)

The kinetics of increased Treg frequencies coincided with the kinetics of lymphoma cell appearance in the three tissues (day 8 in the LNs, day 6…